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#reduction#shingles#health#covid#dementia#risk#population#don#replicated#study

Discussion (11 Comments)Read Original on HackerNews

hereme888β€’6 minutes ago
Replicated association, which is strong, but not proof. Initial study saw a 3.5% absolute reduction in dementia diagnoses over seven years with a very wide confidence interval. In Australia the study was replicated with 1.8% absolute reduction over 7.4 yrs. Canadian replication: 2% over 5.5 yrs.

Infections generally increase the risk of future dementia. Like the more colds you have throughout life.

robot_jesusβ€’21 minutes ago
I'm in my 40s with genetic predisposition for Alzheimer's. Been seriously considering the past year or two paying out of pocket for Shingrix. I think it would be ~$500 total for two doses.

Sure, I could wait 7 or 8 years until I qualify via insurance, but is that really worth the risk for what is an easily absorbed cost to me? Especially when I have a friend in her late 30s who just went through a very rough bout of shingles?

It makes sense to have targets like age 50 for population-wide public health recommendations. But it can and does infect people of much earlier ages.

Recent articles like this make me think I'll go ahead.

cyanydeezβ€’16 minutes ago
aside from age ranges being the tested population, your just gambling no other interference pattern is involved.
swed420β€’4 minutes ago
CTRL+F covid: 0 results

Very shortsighted article in that regard, but that's the new normal.

If people are concerned about brain health, they'd be wise to continue a zero-covid lifestyle into 2026 and beyond, since each re-infection (which vaccines don't prevent) increases the risk of severe health outcomes, including brain-related issues among lots of others. Adding to the confusion, 40% of COVID infections are asymptomatic but carry the same longterm risks.

Yet I only see about .5-1% of the population in my area these days wearing any kind of mask/N95 respirator in public.

Fortunately at least a tiny minority are waking up to this fact, as can be seen by constant growth in communities like /r/zerocovidcommunity and Google Trends data for 'zero covid'.

robot_jesusβ€’27 minutes ago
sowbugβ€’23 minutes ago
Shingles vaccine, if you don't feel like clicking through.
blooalienβ€’13 minutes ago
Thank you.
satya71β€’23 minutes ago
TL;DR Shingles vaccines reduces chances of dementia by 20%. Yet, most countries health systems only look at the upfront cost of ~$300 and don’t recommend for all who could benefit.
MASNeoβ€’7 minutes ago
In a separate article the other factors are quoted with similar impact (listed in order of max potential magnitude) - anti depression treatment - education increases - hearing improvement - obesity reduction - low alcohol

The earlier you start the better.

gruezβ€’4 minutes ago
>anti depression treatment - regular exercise - obesity reduction - education - less/no alcohol

Injecting people with a shingles vaccine is far easier than the others you listed, which is why it stands out.

SoftTalkerβ€’6 minutes ago
20% of what?